Streck Cell-free 游离DNA采血管用于NIPT-红荣微再（上海）生物工程技术有限公司

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Streck Cell-free 游离DNA采血管用于NIPT

更新时间：2018-01-23 点击次数：5016次

NIPT：NIPT ，无创产前筛查，是利用大规模平行测序等技术对母体外周血中的游离 DNA 进行深度测序，获取胎儿染色体信息的方法。传统的产前筛查和诊断方法( 孕早期超声检查、孕中期血清学筛查、羊水细胞染色体核型分析) 均有一定的局限性，尤其穿刺法可能会伤害胎儿导致流产。随着新一代测序技术研究的深入，无创性胎儿基因检测得到了快速发展。

染色体非整倍体：染色体非整倍体是出生缺陷zui常见的遗传性病因，常见类型有 21-三体、18-三体、13-三体、X-三体等。患儿常表现为先天性非进行性智力障碍，生长发育迟缓和( 或)

合并畸形，目前尚无有效的治疗方法。

使用Streck Cell-free DNA BCT采血管进行无创产前筛查的文献：

使用Streck Cell-free DNA BCT采血管采集保存运输孕妇外周血样本。

使用PCR、高通量基因测序等检测方法分析母体血浆中的胎儿游离DNA。

分析是否有常见胎儿遗传病：三体综合征等。

参考文献：

张媛媛,刘晓亮,初国铭,崔婉婷,何蓉,赵彦艳.无创性胎儿常见染色体非整倍体筛查与结果分析[J].山东医药,2017,57(20):1-4.

史晓琳,张志涛,刘彩霞.胎儿染色体非整倍体无创基因检测在孕早期产前筛查的可行性临床应用研究[J].中国优生与遗传杂志,2014,22(03):44-47.

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关键词：

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关键词：产前诊断胎儿游离DNA